Europe 'epicenter' of monkeypox outbreak – WHO

By Agence France-Presse

COPENHAGEN: The World Health Organization (WHO) said Wednesday Europe remained the epicenter of the global monkeypox outbreak, which posed a "real risk" with more than 1,500 cases reported in the region.

The UN health body already announced on Tuesday that it would hold an emergency meeting next week to determine whether to classify the outbreak as a public health emergency of international concern.

"Europe remains the epicenter of this escalating outbreak with 25 countries reporting more than 1,500 cases, or 85 percent of the global total," Hans Kluge, WHO regional director for Europe, told a press conference Wednesday.

WHO's European region comprises 53 countries, including several in Central Asia.

Until the past few months, monkeypox had generally been confined to Western and Central Africa.

Kluge said that the majority of cases reported in Europe "have been among men who have sex with men", but also warned against stigmatisation.

He stressed "that the monkeypox virus is not in itself attached to any specific group."

The regional director also warned that the risk was increasing as summer had arrived with "tourism, various Pride events, music festivals and other mass gatherings planned across the region."

"These events are powerful opportunities to engage with young, sexually active and highly mobile people," Kluge said, but stressed that "monkeypox is not a reason to cancel events, but an opportunity to leverage them to drive our engagement."

Speaking next to Kluge, Steve Taylor, director of European Pride Organisers Association, said that some 750 Pride events were planned across the European region and welcomed the WHO's recommendation not to cancel these events.

"Sadly, but entirely predictably, some of those who oppose Pride and who oppose equality and human rights have already been attempting to use monkeypox as a justification for calls for Pride to be banned," Taylor told reporters.

The EU announced Tuesday that it had purchased almost 110,000 vaccine doses to help tackle the outbreak, though the WHO does not recommend mass vaccination against monkeypox.

No FDA approval yet for monkeypox antivirals — DOH

This undated electron microscopic (EM) handout image provided by the Centers for Disease Control and Prevention depicts a monkeypox virion, obtained from a clinical sample associated with the 2003 prairie dog outbreak. It was a thin section image from a human skin sample. On the left were mature, oval-shaped virus particles, and on the right were the crescents, and spherical particles of immature virions.

Cynthia S. Goldsmith / Centers for Disease Control and Prevention / AFP

By Angelica Y. Yang - Philstar.com

MANILA, Philippines — Department of Health Secretary Francisco Duque III said Saturday that the country's Food and Drug Administration has not yet given approval or authorization for the use of monkeypox antivirals.

Several cases of monkeypox, endemic to Africa, were detected in North American and European countries in early May. To date, the Philippines has no confirmed monkeypox case, although the Health department has said it is intensifying border control measures and actively monitoring the developments. 

"Wala pang approval ng FDA natin. Wala pang emergency use authorization (EUA). Ito 'yung mga legal na batayan para makapagpasok ng mga antivirals against monkeypox," Duque said in an interview with Dobol B TV on Saturday. 

("The FDA has not given its approval. There is also no emergency use authorization yet. These are the legal basis which will allow for the import of antivirals against monkeypox.")

On Friday, DOH said it is participating in talks on the possible acquisition of antivirals in case the country experiences an outbreak or if there are severe cases. 

There is already a monkeypox vaccine which has been developed, but the World Health Organization said it is not yet widely available, DOH said in an earlier statement. 

"The DOH is exploring all possible available sources and expedient legal methods for the procurement of Monkeypox vaccines," the agency told reporters.

Monkeypox vaccination is not yet part of the country's national immunization program. 

Monkeypox can be transmitted to humans after experiencing close contact with an infected individual or animal, or with contaminated materials. Symptoms of the disease include fever, rashes and swollen lymph nodes. 

Govt warning out on 'monkeypox'

By Red Mendoza, Manila Times

(UPDATE) WHILE the rise in Covid-19 cases in Metro Manila is "not alarming" to health experts, the outbreak of a new viral disease called "monkeypox" in parts of the world is enough for the government to warn the public against its spread if health protocols are ignored.

The Department of Health (DoH) has issued a public health advisory on monkeypox after an outbreak was reported in the United States, Canada and the United Kingdom.

Monkeypox, according to the World Health Organization (WHO), is "a viral disease from animals and primarily occurs in the tropical rainforest of Central and Western Africa."

It can be transmitted to humans through "close contact via fluid transmission with an infected person or animal or through contaminated materials," according to WHO.

Symptoms of the disease include "fever, rashes and swollen lymph nodes, which could also lead to medical complications," it said.

"But it is less contagious than smallpox and causes less severe illnesses," it said.

More than 80 cases of the disease have been reported in 11 countries, with the UK having the most since it was first detected in a passenger from Nigeria.

PH reports 8,702 new Covid-19 cases

The DoH, in a public advisory late Friday night, said that although no case of monkeypox has been detected in the country or its borders, health screening has been intensified and surveillance systems are in place.

The DoH said that minimum public health standards currently enforced against Covid-19 such as "wearing your best-fitted mask, ensuring good airflow, keeping hands clean and physical distancing" will also prevent the spread of monkeypox in the country.

In a separate briefing, Dr. Teodoro Herbosa, emergency medicine specialist, said that monkeypox is different from the Covid virus as its method of transmission is different.

He said that the smallpox vaccine, which has not been produced since the eighties, can be used to prevent a possible spread of monkeypox.

Herbosa said the country's borders should not be closed even with the detection of monkeypox in other countries, noting that public health measures will be enough to prevent the spread of the disease without hurting the economy.

"Ang pagsara ng borders, malaki ang epekto nito sa turismo at ekonomiya at supply chain ng ating mga goods and services, [so] hindi tama na mag-close down (Closing the borders will have a huge impact on tourism, the economy, and the supply chain of goods and services, so it is not right that we close down)," Herbosa added.

Meanwhile, the independent OCTA Research group downplayed the increase in the number of Covid cases in the National Capital Region (NCR).

OCTA said on Friday that cases in the region increased by 19 percent to 71 cases per day during the week of May 13 to 19, higher than the 59 daily cases the week before.

It also noted an increase in the average daily attack rate to 0.50 cases per 100,000 individuals, while the reproduction number increased to 0.9 from 0.76.

Herbosa, the special adviser for the National Task Force Against Covid-19, assured that there was no cause for alarm for as long as the source can be determined and to make sure that the infected are isolated to contain the spread.

Herbosa also said that the government aims to administer the second booster shots to about 12 million senior citizens and health care workers by the end of the month.

He urged the next administration to continue the national Covid-19 program blueprint implemented by the Duterte administration because it has been effective in containing the spread of the virus.

"Magbibigay tayo ng magandang operational plan at ang National Action Plan Phase 5, hopefully 'yung susunod na administrasyon papalawakin pa [para sa] ating economic recovery (We will give a good operational plan and we hope that the National Action Plan Phase 5 will be continued and expanded by the next administration for our economic recovery," Herbosa said.

Omicron subvariant detected

Even as health experts downplay the Covid increase in the NCR, a Filipino who arrived in the country from the Middle East last May 4 was found positive for the BA.4 sublineage of the Omicron variant four days after he planed in.

This comes amid the detection of other sublineages of Omicron, such as BA.2.12 and BA.2.12.1, in the country.

No other details were shared except that he was asymptomatic.

"The immediate priority is to ensure the case has been cared for and his close contacts quarantined to interrupt transmission," the DoH said.

The European Centre for Disease Prevention and Control has classified the BA.4 sublineage as a variant of concern due to its capacity to either spread faster or cause worse illness.

Early studies suggested that BA.4 transmits faster because of its ability to evade immunity provided by vaccines, especially for those whose protection had waned over time.

The DoH has coordinated with concerned local government units to implement detection and isolation activities, as well as seek out those unvaccinated and those eligible for boosters.

Ivermectin trials terminated

In a related development, the Department of Science and Technology (DoST) said that it has terminated the clinical trials of the anti-parasitic drug ivermectin as a possible cure for Covid-19.

According to Science and Technology Secretary Fortunato de la Peña, the decision was made upon the recommendation of the DoH and the DoST-Philippine Council for Health Research and Development governing council in its meeting on May 11.

De la Peña cited delays in the submission of deliverables, lack of clinical benefits of ivermectin based on more recent clinical studies, the issuance of the recommendation against the use of the drug, and the availability of effective therapeutics for the early phase of Covid-19.

Last year, President Rodrigo Duterte ordered the clinical trials amid increased clamor by several lawmakers and groups who claimed that the anti-parasitic drug would be helpful in preventing early-stage