- The ‘glymphatic system’ — the flow of cerebrospinal fluid during sleep to flush out toxins and waste materials from the brain — plays an essential role in keeping the brain healthy.
- A new study, using MRI scans, found that people with cardiovascular risk factors that impaired the function of the glymphatic system had an increased risk of dementia.
- The researchers suggest that improving sleep patterns to enhance glymphatic system function and treating cardiovascular risks could both help reduce dementia risk.
The glymphatic system is a recently discovered waste clearance system, most active during sleep, that removes toxins and waste materials, including those associated with dementia, from the
A new study has found that people with an impaired glymphatic system have a higher risk of developing dementia.
The study, published in
“These findings are largely expected, building on a growing body of research that implicates impaired
cerebrospinal fluid (CSF) dynamics, often referred to as the ‘glymphatic system’, in dementia. Animal studies have long shown that disrupted CSF flow hampers the clearance of toxic proteins such as amyloid beta and tau, which are central to Alzheimer’s disease pathology. What makes this study significant is that it provides large-scale, human-based evidence from over 45,000 participants in the UK Biobank, confirming that MRI markers of CSF dysfunction […] are associated with higher dementia risk.”— Dr Steve Allder, consultant neurologist at Re:Cognition Health, who was not involved in the study.
No comments:
Post a Comment